CRYSTALLINE POLYMORPH OF 15B-HYDROXY-OSATERONE ACETATE

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专利权人:

LTD.;ASKA PHARMACEUTICAL CO.

发明人:

NAKAGAWA Takayoshi,HAYASHI Hiroyuki,MIYAZAKI Koichi,IWASHITA Shigeki

申请号：

PH12018502365

公开号：

PH12018502365A1

申请日:

2018.11.09

申请国别(地区):

PH

年份:

2019

代理人:

摘要：

Provided is a crystalline polymorph A of 15#-hydroxy-osaterone acetate having improved stabilities (storage stability,pulverization stability, and absorption property). Diffraction peaks characteristic of this crystalline polymorph A of 15#-hydroxyosaterone acetate, in a powder X-ray diffraction spectrum, appear at diffraction angles 2# of 9.6øñ0.2ø, 17.1øñ0.2ø, and 20.2øñ0.2ø. The crystalline polymorph A has a melting point of 280-283øC, and is a prismatic crystal.

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