PROBLEM TO BE SOLVED: To provide a composition for optic nerve protection and optic nerve regeneration.SOLUTION: A composition useful for optic nerve protection and optic nerve regeneration comprises a water-insoluble polymer with a degree of polymerization of 10 or more, selected from a homopolymer of β-hydroxybutyric acid or a copolymer of β-hydroxybutyric acid and C3-C12 β-hydroxy saturated fatty acid, and is administered by oral administration or a similar administration method.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】視神経保護、並びに視神経再生のための組成物の提供。【解決手段】β-ヒドロキシ酪酸の単独重合体又はβ-ヒドロキシ酪酸と炭素数3~12のβ-ヒドロキシ飽和脂肪酸との共重合体から選択される重合度10以上の水不溶性重合体を含み、経口投与又は経口投与に類する投与方法によって投与される、視神経の保護及び視神経再生に有用な組成物。【選択図】なし