DUBENSKY, Thomas, W., Jr. TW,‧小杜本斯蓋,KANNE, David, B. DB,‧坎恩
申请号：
HK16105734.2
公开号：
HK1217606A
申请日:
2016.05.18
申请国别(地区):
HK
年份:
2017
代理人:
摘要：
The present invention provides cyclic-di-nucleotide (CDN) compounds that inhibit signaling at a recently discovered cytoplasmic receptor known as STING (Stimulator of Interferon Genes). In particular, the CDNs of the present invention are provided in the form of a composition comprising one or more cyclic purine dinucleotides which inhibit STING-dependent TBK1 activation and the resulting production of type I interferon.
