THE PROVOST; FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVED TRINITY OF QUEEN ELIZABETH
发明人:
FARRAR, GWYNETH JANE,MILLINGTON-WARD, SOPHIA,CHADDERTON, NAOMI,PALFI, ARPAD,O'REILLY, MARY,KENNA, PAUL,HUMPHRIES, PETER
申请号:
CA2683469
公开号:
CA2683469C
申请日:
2008.04.14
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The invention relates to gene suppression and replacement. In particular, the invention relates to enhanced expression of suppression agents for suppressing gene expression in a cell and in vivo and replacement nucleic acids that are not inhibited by the suppression agent. Regulatory elements are included in expression vectors to optimize expression of the suppression agent and/or replacement nucleic acid.