Provided is an agent for improving dry eye that has a strong effect and few side effects. An agent for improving dry eye or an agent for suppressing MCP-1 expression has as an active ingredient dipivefrin or adrenaline.本發明係提供一種效果較強,且副作用較少之乾眼症改善劑。 本發明係一種以地匹福林或腎上腺素作為有效成分之乾眼症改善劑或MCP-1表現抑制劑。