DODD, STEPHANIE KAY,FURET, PASCAL,GROTZFELD, ROBERT MARTIN,JAHNKE, WOLFGANG,JONES, DARRYL BRYNLEY,MANLEY, PAUL,MARZINZIK, ANDREAS,PELLE, XAVIER FRANCOIS ANDRE,SALEM, BAHAA,SCHOEPFER, JOSEPH
申请号:
SG11201407152X
公开号:
SG11201407152XA
申请日:
2013.05.09
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.