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Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1
专利权人:
NOVARTIS AG
发明人:
FURET PASCAL,DODD STEPHANIE KAY,GROTZFELD ROBERT MARTIN,JAHNKE WOLFGANG,JONES DARRYL BRYNLEY,MANLEY PAUL,MARZINZIK ANDREAS,PELLE XAVIER FRANCOIS ANDRE,SALEM BAHAA,SCHOEPFER JOSEPH
申请号:
NZ70162613
公开号:
NZ701626A
申请日:
2013.05.09
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.
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