ZOLTN SZABO,ANDRS KOTSCHY,OLIVIER GENESTE,MRTON CSEKEI,GBOR RADICS,BALZS BALINT,JAMES EDWARD PAUL DAVIDSON,ZOLTN SZLAVIK,JAMES BROOKE MURRAY,I CHEN,ATTILA JEN - PACZAL,SZABOLCS SIPOS,AGNES PROSZENYAK
申请号：
ARP140104847
公开号：
AR098906A1
申请日:
2014.12.22
申请国别(地区):
AR
年份:
2016
代理人:
摘要：
Compounds useful in the treatment of Cancer and autoimmune diseases.Claim 1: Compound of formula (1), in which: c u2081 u208b u2086 represents a linear or branched alkyl group, a group alquenilo c u2082 u208b u2086 linear or branched, a group Alquinilo c u2082 u208b u2086 linear or branched alkoxy Group c u2081 u208b u2086, a linear or branched alkyl group c u2081 u208b u2086 -, S -, or N polihaloalquilo c u2081 u208b u2086 linear or branched, a Hydroxy Group, a cyano -, - nr u00b9 u2070r u00b9 u2070, cy u2076 or a Halogen Atom； r u00b9, R u00b2, r u00b3,R u2074 r u2075 independently of each other and represent a hydrogen Atom, a Halogen Atom, a linear or branched alkyl group c u2081 u208b u2086 alquenilo c u2082 u208b u2086 Group, a linear or branched, a group Alquinilo c u2082 u208b u2086 linear or linear or branched, a polihaloalquilo c u2081 u208b u2086 ramif Qualified, a Hydroxy Group, a Group c u2081 u208b u2086 linear or branched alkoxy -, S - c u2081 u208b u2086 alkyl group, a cyano Group, a NitroC u2080 u208b u2086 nr u2078r u2078 - alkyl -, - or - cy u00b9, c u2080 u208b u2086 cy u00b9 - alkyl -, - alquenilo c u2082 u208b u2086 - cy u00b9 alquinilo cy u00b9 c u2082 u208b u2086 -, -, - or - r u2079 c u2081 u208b u2086 alkyl, - C (o) - or u2078, or r u2078 - C (o) -, - C (o) - nr u2078r u2078, - nr u2078 - C (o) - r u2078 nr u2078 -, - C (o) - - - nr u2078 c u2081 u208b u2086 or u2078 alkyl, - C (o) - r u2078, - - - - SO u2082 nr u2078r u2078, SO u2082 alkyl Or c u2081 u208b u2086 or substituents of the Pairs (r u00b9, R u00b2), (R u00b2, r u00b3), (r u00b9, r u00b3), (r u2074, r u2075) when grafted on two adjacent carbon Atoms.Form along with the carbon Atoms to which are attached to an Aromatic Ring or Aromatic Compound by 5 to 7 members in the ring, which can contain one to three heteroatoms selected from Oxygen, Sulfur and Nitrogen, with the resulting Ring may be substituted With a selected Group of a linear or branched alkyl group c u2081 u208b u2086, n
