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Piperidinilo Derivatives with aryl substituted (hetero), a process for their Preparation and Pharmaceutical compositions containing them
专利权人:
LES LABORATOIRES SERVIER
发明人:
DEMARLES, DIDIER,CHANRION, MAA,GENESTE, OLIVIER,IVANSCHITZ, LISA,LEWKOWICZ, ELODIE,MURRAY, JAMES BROOKE,MACIAS, ALBA,KISS, RPD,VASAS, ATTILA,WBER, CSABA,KOTSCHY, ANDRS,MOLNR, BALZ
申请号:
ARP170101586
公开号:
AR108705A1
申请日:
2017.06.09
申请国别(地区):
AR
年份:
2018
代理人:
摘要:
Claim 1: Compound of formula (1), in which: r\u00b9 represents an aryl group or a heteroaryl Group R\u00b2 represents a hydrogen Atom or a Halogen Atom and N is an integer equal to 0.1 or 2 J represents a Group - C (o) -, a Group (- ch - r\u00b3)Or a Group - SO\u2082 r\u00b3 represents a hydrogen Atom or a linear or branched alkyl group c\u2081\u208b\u2086 K represents a link or a cy\u00b9 Group l represents a group or a Group ch\u2082 cy\u00b2 - - - cy\u00b2 W representTo the group of formula (2), which represents a heteroaryl Ring: X represents a carbon Atom or a nitrogen Atom r\u2074 represents a hydrogen Atom, a Halogen Atom,A c\u2081\u208b\u2086 linear or branched alkyl group, a group alquenilo c\u2082\u208b\u2086 linear or branched, a group Alquinilo c\u2082\u208b\u2086 linear or branched, a group y\u00b9 nr\u2076r\u2077 - - - -, a group y\u00b9 or\u2076,A group haloalquilo c\u2081\u208b\u2086 linear or branched, an oxo Group, a group y\u00b9 - cy\u00b3, a Group cy\u00b3 r\u2077 - - - - or\u2077 cy\u00b3, a Group, or a Group - y\u00b9 - nr\u2076 - C (o) - r\u2077 r\u2075 represents a hydrogen Atom,A Halogen Atom, or a linear or branched alkyl group c\u2081\u208b\u2086 r\u2076 represents a hydrogen Atom or a linear or branched alkyl group c\u2081\u208b\u2086 r\u2077 represents a hydrogen Atom,A linear or branched alkyl group c\u2081\u208b\u2086,Or a Group - y\u00b2 - cy\u2074 y\u00b9 y\u00b2 independently of each other and represent a link or a group alquileno c\u2081\u208b\u2084 linear or branched cy\u00b9 represents a cycloalkyl Group, a Group heterocicloalquilo,An aryl or heteroaryl Group, a group that is attached to the group and the Group l J cy\u00b2, cy\u00b3 and cy\u2074 independently of one another, represent a cycloalkyl Group, a Group heterocicloalquilo,A group or an aryl, heteroaryl Group as \"aryl\" means a group phenyl, naphthyl,\"Indanilo or heteroaryl\" means any group consisting of FUSED bicyclic mono or 5 to 10 members in the ring,You have at
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