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γ-secretase inhibitor
专利权人:
Atsuhiro Abe;Hiroshi Kodaira;Hideaki Shimizu;Seigo Sawada
发明人:
Atsuhiro Abe,Hideaki Shimizu,Seigo Sawada,Hiroshi Kodaira
申请号:
US12672326
公开号:
US08501813B2
申请日:
2008.07.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
It is intended to provide a novel compound that has an excellent γ-secretase inhibitory effect and specifically inhibits Aβ production.The present invention provides a compound of the following formula (1) or a pharmaceutically acceptable salt thereof: wherein R1 represents a linear or branched alkyl group having 1 to 4 carbon atoms or a phenyl group; R2 represents a linear or branched alkyl group having 1 to 4 carbon atoms which may be substituted by one or more phenyl or halogenophenyl groups; R3 represents a linear or branched alkyl group having 1 to 4 carbon atoms which may be substituted by one or more hydroxyl groups; R4 represents a linear or branched alkyl group having 1 to 4 carbon atoms; and the symbol “*” represents a chiral center.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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