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GAMMA-SECRETASE INHIBITOR
专利权人:
发明人:
申请号:
EP08790127.8
公开号:
EP2177529B1
申请日:
2008.07.01
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
It is intended to provide a novel compound that has an excellent γ-secretase inhibitory effect and specifically inhibits Aβ production.The present invention provides a compound of the following formula (1) or a pharmaceutically acceptable salt thereof: wherein R1 represents a linear or branched alkyl group having 1 to 4 carbon atoms or a phenyl group R2 represents a linear or branched alkyl group having 1 to 4 carbon atoms which may be substituted by one or more phenyl or halogenophenyl groups R3 represents a linear or branched alkyl group having 1 to 4 carbon atoms which may be substituted by one or more hydroxyl groups R4 represents a linear or branched alkyl group having 1 to 4 carbon atoms and the symbol "*" represents a chiral center.
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