KOIKE, MASAMICHI,SPITALNY, GEORGE L.,WHEELER, ALISTAIR,WHITE, BARBARA
申请号：
CA2986531
公开号：
CA2986531C
申请日:
2008.05.14
申请国别(地区):
CA
年份:
2020
代理人:
摘要：
The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g., esophagus, stomach, small intestine and colon), or lung.
