Masamichi Koike,George L. Spitalny,Alistair Wheeler,Barbara White
申请号：
US13934271
公开号：
US09815895B2
申请日:
2013.07.03
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.
