Koike, Masamichi,Spitalny, George L,Wheeler, Alistair,White, Barbara
申请号:
AU2013273774
公开号:
AU2013273774B2
申请日:
2013.12.20
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2013273774B220160915.pdf#####Abstract The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e g, esophagus, stomach, small intestine and colon), or lung.