KOIKE, MASAMICHI,SPITALNY, GEORGE L.,WHEELER, ALISTAIR,WHITE, BARBARA
申请号:
CA2685222
公开号:
CA2685222C
申请日:
2008.05.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to a method of reducing the numbers ofeosinophils in a human subject comprisingadministration to a subject an IL-5R binding molecule that comprises (a) aregion that specifically binds to the IL-5R and (b) animmunoglobulin Fc region. In a specific embodiment, a method of the inventionreduces the number of eosinophils in blood, bonemarrow, gastrointestinal tract (e g, esophagus, stomach, small intestine andcolon), or lung.