Spitalny, George L.,Koike, Masamichi,White, Barbara,Wheeler, Alistair
申请号:
AU2008255027
公开号:
AU2008255027B2
申请日:
2008.05.14
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to a method of reducing the numbers of eosinophilsin a human subject comprising administration to a subject an IL-5R binding moleculethat comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulinFc region. In a specific embodiment, a method of the invention reduces the numberof eosinophils in blood, bone marrow, gastrointestinal tract (e g, esophagus,stomach, small intestine and colon), or lung.