HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE;THE UNIVERSITY OF QUEENSLAND
发明人:
ROSENGREN, KARL JOHAN,HAUGAARD-KEDSTROM, LINDA MARIA,BATHGATE, ROSS ALEXANDER DAVID,HOSSAIN, MOHAMMED AKHTER,WADE, JOHN DESMOND,GUNDLACH, ANDREW LAWRENCE,LAWRENCE, ANDREW J.
申请号：
CA2813802
公开号：
CA2813802C
申请日:
2011.09.08
申请国别(地区):
CA
年份:
2020
代理人:
摘要：
The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are antagonists of the RXFP3 receptor, and in some embodiments are selective antagonists of the RXFP3 receptor.
