Karl Johan Rosengren,Linda Maria Haugaard-Kedstrom,Ross Alexander David Bathgate,Mohammed Akhter Hossain,John Desmond Wade,Andrew Lawrence Gundlach,Andrew J. Lawrence
申请号：
US13821726
公开号：
US09359422B2
申请日:
2011.09.08
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are antagonists of the RXFP3 receptor, and in some embodiments are selective antagonists of the RXFP3 receptor.
