Rosengren, Karl Johan,Haugaard-Kedstrom, Linda Maria,Bathgate, Ross Alexander David,Hossain, Mohammed Akhter,Wade, John Desmond,Gundlach, Andrew Lawrence,Lawrence, Andrew J.
申请号：
AU2011301146
公开号：
AU2011301146A1
申请日:
2011.09.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are antagonists of the RXFP3 receptor, and in some embodiments are selective antagonists of the RXFP3 receptor.
