CHARRIER, JEAN-DAMIEN,MAZZEI, FRANCESCA,KAY, DAVID,MILLER, ANDREW
申请号:
HK05108425.3
公开号:
HK1077057B
申请日:
2005.09.23
申请国别(地区):
HK
年份:
2012
代理人:
摘要:
The present invention provides a facile process for the preparation of tri- and tetra-substituted pyrimidines. The process is useful for preparing inhibitors of protein kinases, especially Aurora kinase. These inhibitors are useful for treating or lessening the severity of Aurora-mediated diseases or conditions.