PYRIMIDINE COMPOUNDS AS INHIBITORS OF PROTEIN KINASES IKK EPSILON AND/OR TBK 1 PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
PERRIOR TREVOR ROBERT,NEWTON GARY KARL,STEWART MARK RICHARD,AQIL REHAN
申请号：
IN401/DELNP/2013
公开号：
IN2013DN00401A
申请日:
2013.01.14
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
C Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases associated with aberrant activity of the protein kinases ???e and/or TBK 1 : in which: R represents an aliphatic heterocyclyl group having 4 5 6 or 7 ring atoms bonded to the phenyl group shown in formula I through a ring nitrogen atom and optionally substituted by one or more substituents defined in the Specification R represents a phenyl or heteroaryl group which is optionally substituted by one or more substituents defined in the Specification and each of R and R independently represents a hydrogen atom or a C alkyl group.
