Jean-Damien Charrier,Francesca Mazzei,David Kay,Andrew Miller
申请号：
US12436407
公开号：
US08268829B2
申请日:
2009.05.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides a facile process for the preparation of tri- and tetra-substituted pyrimidines. The process is useful for preparing inhibitors of protein kinases, especially Aurora kinase. These inhibitors are useful for treating or lessening the severity of Aurora-mediated diseases or conditions.
