Rodriguez Vincente, Alberto,Garcia-Lbarrola, Maria Garranzo,Sancho, Francisco Sánchez,Marchante, Carmen Cuevas,Urbano, Christina Mateo,Juárez, Isabel Digón
申请号:
ES13154647
公开号:
ES2578606T3
申请日:
2008.12.19
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
A compound of general formula I ** Formula ** in which Y is selected from -CHRay-, -CHRay-CHRby-, -CRay>; = CRby-, -C≡C-, -CHRay-CHRby-CHRcy-, - CHRay-CRby>; = CRcy- and -CHRay-C≡C-; each Ray, Rby and Rcy is independently selected from hydrogen, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl and substituted or unsubstituted C2-C12 alkynyl; each R1, R2, R3, R4 and R5 are independently selected from hydrogen, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl and substituted or unsubstituted C2-C12 alkynyl; R6 is selected from NR8R9 and OR10; A is ** Formula ** W is selected from O and NR7; R7 is selected from hydrogen, CORa, COORa, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl and substituted or unsubstituted C2-C12 alkynyl, or R7 and R5, together with the atom of N and the atom of C corresponding to those that are attached can form a substituted or unsubstituted heterocyclic group; R8 is selected from hydrogen, CORa, COORa, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl, substituted or unsubstituted C2-C12 alkynyl, substituted or unsubstituted C4-C12 alkenyl; R10 is selected from hydrogen, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl and substituted or unsubstituted C2-C12 alkynyl; each dotted line represents an optional link, but when there is a triple bond between the atoms of C to which R1 and R2 are attached, R1 and R2 are absent, and when there is a triple bond between the atoms of C to which they are joined R3 and R4, R3 and R4 are absent; R9 is selected from hydrogen, CORa, COORa, substituted or unsubstituted C1-C12 alkyl, substituted or unsubstituted C2-C12 alkenyl, substituted or unsubstituted C2-C12 alkynyl and substituted or unsubstituted C4-C12 alkenyl; each R16, R17 and R18 is independently selected from hydrogen, ORa, OCORa, OCOORa, NRaRb, NRaCORb and N