Disclosed is a process for producing compound C represented by formula C: wherein R' represents straight chain, branched chain, or cyclic C 2-6 alkylcarbonyl, wherein R 1b is used as a protective group for hydroxyl at the 7-position of compound C. R 1b represents formyl； optionally substituted straight chain C 1-4 alkylcarbonyl； optionally substituted benzyl； group -SiR 3 R 4 R 5 optionally substituted by halogen atom wherein R 3 , R 4 , and R 5 each independently represent straight chain or branched chain C 1-6 alkyl or phenyl； C 1-6 alkyloxy-C 1-6 alkyl optionally substituted by halogen atom； C 1 - 6 alkylthio-C 1-6 alkyl optionally substituted by halogen atom； straight chain, branched chain, or cyclic C 1-4 alkyl optionally substituted by halogen atom, provided that, when alkyl in the C 1-4 alkyl group is of a branched chain or cyclic type, the alkyl group is C 3-4 alkyl； C 2-6 alkenyl optionally substituted by halogen atom； C 2-6 alkynyl optionally substituted by halogen atom； or an optionally substituted saturated or unsaturated five- or six-membered heterocyclic group. The process can produce pyripyropene derivatives that have acyloxy groups at the 1- and 11-positions and a hydroxyl group at the 7-position and are useful as insect pest control agents at a high yield.本發明係提供一種方法，其係以下式C[式中，R'為直鏈、分枝鏈、或環狀之C2－6烷基羰基]所示之化合物C之製造方法；其特徵係於第7位置之羥基之保護基，使用R1b[R1b係甲醯基、可被取代之直鏈C1－4烷基羰基、可被取代之苄基、可以鹵原子取代之－SiR3R4R5基(其中，R3、R4及R5係彼此獨立地為直鏈或分枝鏈狀之C1－6烷基、或苯基)、可以鹵原子取代之C1－6烷基氧基－C1－6烷基、可以鹵原子取代之C1－6烷基硫－C1－6烷基、可以鹵原子取代之直鏈、分枝鏈或環狀之C1－4烷基(該基為分枝鏈或環狀時，為C3－4烷基)、可以鹵原子取代之C2－6鏈烯基、可以鹵原子取代之C2－6炔基、或可被取代之飽和或不飽和之5或6員之雜環基]者。根據該方法，可以高產率製造在第1及11位置上具有醯基氧基，且在第7位置上具有羥基，可作為有用的除害蟲劑之比利比洛邊(PYRIPYROPEN)衍生物。
