Provided is a method for preventing and/or reducing the abnormal deposition of lipid in tissues and organs of the body of a subject, comprising administering an effective amount of plasminogen to a subject. Also provided are a medicine, pharmaceutical composition, product, and kit comprising plasminogen and used for preventing and/or reducing the abnormal deposition of lipid in tissues and organs of the body of a subject.本發明涉及預防和/或消減受試者脂肪在身體組織器官異常沉積的方法,包括給藥受試者有效量的纖溶酶原。本發明還涉及用於預防和/或消減受試者脂肪在身體組織器官異常沉積的包含纖溶酶原的藥物、藥物組合物、製品、試劑盒。