A method for preventing and/or treating fatty liver and related diseases thereof of a subject, comprising administering an effective amount of plasminogen to a subject. In addition, the present invention also relates to a medicine, pharmaceutical composition, product, and kit comprising plasminogen and used for preventing and/or treating fatty liver and related diseases thereof of a subject.本發明涉及一種預防和/或治療受試者脂肪肝及其相關病症的方法,包括給藥受試者有效量的纖溶酶原;另一方面,本發明還涉及用於預防和/或治療受試者脂肪肝及其相關病症的包含纖溶酶原的藥物、藥物組合物、製品、試劑盒。