The present invention pertains to: an anti-human CRTH2 antibody which specifically recognizes and binds to human CRTH2 a fragment of the antibody DNA which encodes the amino acid sequence of the antibody a vector including the DNA an antibody-producing cell and a hybridoma which produce the antibody a production method for the antibody a composition which includes the antibody or antibody fragment a treatment method and a diagnostic method which use the antibody or antibody fragment for diseases, such as allergenic diseases, autoimmune diseases, diseases associated with eosinophilia and hyperfunction, and diseases associated with an increase in and/or hyperfunction of Th2 cells and a medicine and a diagnostic agent which include the antibody or antibody fragment.本發明係關於一種特異性識別人類CRTH2並與之結合之抗人類CRTH2抗體、該抗體片段、編碼該抗體之胺基酸序列之DNA、包含該DNA之載體、生產該抗體之融合瘤及抗體生產細胞、該抗體之製造方法、包含該抗體或抗體片段之組合物、使用該抗體或抗體片段之過敏性疾病、自體免疫疾病、伴有嗜酸性球增多或功能亢進之疾病、伴有Th2細胞增多或功能亢進之疾病等之治療方法及診斷方法、以及包含該抗體或抗體片段之醫藥及診斷藥。
