The instant disclosure provides antibodies that specifically bind to CD137 (e.g., human CD137) and increases CD137 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.本揭示案提供特異性結合於CD137(例如人類CD137)且增加CD137功能之抗體。亦提供包含此等抗體之醫藥組合物、編碼此等抗體之核酸、用於製造此等抗體之表現載體及宿主細胞以及使用此等抗體治療受試者之方法。