Amos B. Smith, III,Zhuqing Liu,Anne-Marie L. Hogan,Doralyn S. Dalisay,Tadeusz F. Molinski
申请号:
US13386783
公开号:
US20130030027A1
申请日:
2010.07.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to hemi phorboxazole A: and its stereoisomers, as well as derivatives of hemi phorboxazole A of formula I: wherein ring A is aryl or a 5- or 6-membered heteroaryl optionally substituted with one or more of halogen, —OH, or —C1-6alkyl and R is —CN, a 5- or 6-membered heteroaryl, or halogen and the pharmaceutically acceptable salt forms thereof, in addition to methods of using these compounds.