SPIRO-OXINDOLE MDM2 ANTAGONISTS

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专利权人:

Sanofi;The Regents of the University of Michigan;Ascenta Licensing Corporation

发明人:

Shaomeng Wang,Yujun Zhao,Wei Sun,Sanjeev Kumar,Lance Leopold,Laurent Debussche,Cedric Barriere,Jean-Christophe Carry,Kwame Amaning

申请号：

US14170101

公开号：

US20140148494A1

申请日:

2014.01.31

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/