Antagonists of MDM2 - Spiro oxindole

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专利权人:

SANOFI;THE REGENTS OF THE UNIVERSITY OF MICHIGAN;ASCENTA LICENSING CORPORATION

发明人:

WANG, SHAOMENG,ZHAO, YUJUN,SUN, WEI,KUMAR, SANJEEV,LEOPOLD, LANCE,DEBUSSCHE, LAURENT,BARRIERE, CEDRIC,CARRY, JEAN-CHRISTOPHE,AMANING, KWAME,GUO, MING

申请号：

CR20130271

公开号：

CR20130271A

申请日:

2013.06.07

申请国别(地区):

CR

年份:

2013

代理人:

摘要：

Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/