SANOFI;ASCENTA LICENSING CORP;THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人:
WANG SHAOMENG,ZHAO YUJUN,SUN WEI,KUMAR SANJEEV,LEOPOLD LANCE,DEBUSSCHE LAURENT,BARRIERE CEDRIC,CARRY JEAN-CHRISTOPHE,AMANING KWAME,GUO MING
申请号:
ZA201304042
公开号:
ZA201304042B
申请日:
2013.06.03
申请国别(地区):
ZA
年份:
2014
代理人:
摘要:
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.