Spiro-oxindole MDM2 antagonists

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专利权人:

Sanofi;The Regents of the University of Michigan;Ascenta Licensing Corporation

发明人:

Wang, Shaomeng,Zhao, Yujun,Sun, Wei,Kumar, Sanjeev,Leopold, Lance,Debussche, Laurent,Barriere, Cedric,Carry, Jean-Christophe,Amaning, Kwame,Guo, Ming

申请号：

AU2011326395

公开号：

AU2011326395B2

申请日:

2011.11.11

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/