SPIRO-OXINDOLE MDM2 ANTAGONISTS

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专利权人:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人:

ZHAO YUJUN,SUN WEI,KUMAR SANJEEV,LEOPOLD LANCE,BARRIERE CEDRIC,CARRY JEAN-CHRISTOPHE,AMANING KWAME,GUO MING,DEBUSSCHE LAURENT

申请号：

TN2013000202

公开号：

TN2013000202A1

申请日:

2013.05.08

申请国别(地区):

TN

年份:

2014

代理人:

摘要：

Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/