WOZNEY, JOHN MARTIN,SEEHERMAN, HOWARD,BROWN, CHRISTOPHER TODD
申请号：
CA2972970
公开号：
CA2972970A1
申请日:
2015.04.06
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
