BERASI, STEPHEN PETER,BROWN, CHRISTOPHER TODD,CAIN, MICHAEL JOHN,CALABRO, VALERIE PERRINE,JUO, ZONG SEAN,MARTINEZ, ROBERT VINCENT PAUL,SEEHERMAN, HOWARD JOEL,WOZNEY, JOHN MARTIN
申请号：
SG2013005285
公开号：
SG187589A1
申请日:
2011.08.17
申请国别(地区):
SG
年份:
2013
代理人:
摘要：
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
