John Wozney,Howard Seeherman,Christopher Todd Brown
申请号:
US15820527
公开号:
US20180072787A1
申请日:
2017.11.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.