BERASI, Stephen Peter,BROWN, Christopher Todd,CAIN, Michael John,JUO, Zong Sean,MARTINEZ, Robert Vincent Paul,SEEHERMAN, Howard Joel,WOZNEY, John Martin,CALABRO, Valerie Perrine
申请号:
EP17209849
公开号:
EP3320913A3
申请日:
2011.08.17
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.