John Wozney,Howard Seeherman,Christopher Todd Brown
申请号：
US14679705
公开号：
US09856305B2
申请日:
2015.04.06
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
