MACDONALD, Lynn,MURPHY, Andrew, J.,MCWHIRTER, John,TU, Naxin,VORONINA, Vera,GURER, Cagan,MEAGHER, Karolina,STEVENS, Sean
申请号:
EP12784833
公开号:
EP2771357B1
申请日:
2012.10.26
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The invention provides a genetically modified non-human animal that comprises in its genome unrearranged T cell receptor variable gene loci, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.