Lynn MACDONALD,Andrew J. MURPHY,John MCWHIRTER,Naxin TU,Vera VORONINA,Cagan GURER,Karolina MEAGHER,Sean STEVENS
申请号:
US13661342
公开号:
US20130109053A1
申请日:
2012.10.26
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides a genetically modified non-human animal that comprises in its genome unrearranged T cell receptor variable gene loci, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.