Macdonald, Lynn,Murphy, Andrew J.,McWhirter, John,Tu, Naxin,Voronina, Vera,Gurer, Cagan,Meagher, Karolina A.,Stevens, Sean
申请号:
AU2018204700
公开号:
AU2018204700A1
申请日:
2018.06.28
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018204700A120180719.pdf#####ABSTRACT The invention provides a genetically modified non-human animal that comprises in its genome unrearranged T cell receptor variable gene loci, as well as non-human embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.