MacDonald, Lynn,MacDonald, Lynn,Murphy, Andrew J.,Murphy, Andrew J.,McWhirter, John,McWhirter, John,TU, Naxin,TU, Naxin,Voronina, Vera,Voronina, Vera,Gurer, Cagan,Gurer, Cagan,Meagher, Karolina,Meaghe
申请号:
HRP20181626
公开号:
HRP20181626T1
申请日:
2018.10.10
申请国别(地区):
HR
年份:
2018
代理人:
摘要:
The invention provides a genetically modified non-human animal that comprises in its genome unrearranged T cell receptor variable gene loci, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.