Described herein are methods for treating transthyretin (TTR) amyloidosis in a subject. The methods include specific dosing regimens that have great efficacy in treating the subjects and that are well tolerated in subjects.本發明描述用於治療個體之甲狀腺素轉運蛋白(TTR)澱粉樣沉積症的方法。該等方法包括在治療個體方面具有極大功效且在個體中具有良好耐受性之特定給藥方案。