A tablet splitting apparatus capable of reducing fluctuations in weight of split tablet pieces even with simple advanceable-retractable blades is provided. A holding mechanism holds a tablet to be split at a cutting position. In reducing the gap between a pair of opposed blades, which are advanced and retracted with respect to the cutting position, to cut the tablet, the holding mechanism continuously holds the tablet until the tablet is caught between the pair of opposed blades of a cutting mechanism. After the tablet is caught between the pair of opposed blades, the holding mechanism release the tablet and only the pair of opposed blades hold the tablet. The opposed blades are caused to cut into the tablet after the holding mechanism releases the tablet, preventing a crack caused in the tablet ahead of the opposed blades from being curved or increased.