A precision incision device, suitable for use on a human patient during surgery, comprises, in an embodiment, a pair of rails on which a cutting mechanism is slidably positioned. The rails are adhesively affixed to the body for at least the duration of the surgery. Maintained within the cutting mechanism is a blade or similar incising device. The blade is maintained in either of two positions: a retracted position, such that no sharp surface is exposed to a user, or an incising position, when the blade extends down beyond the rail to cause an incision in the patient. Following completion of the surgical procedure, a closure cover is affixed to the pair of rails to close the incision without the need for foreign bodies such as staples or stitches. In an alternative embodiment, only a single rail is required.