COPMANS ALEX HERMAN,HOET JEROME ALBERT JOSEPH,WILLEMSENS ALBERT LOUIS ANNA,VAN DUN JOANNES PETRUS,COUCK WOUTER LOUIS J
申请号：
IN2630/MUMNP/2011
公开号：
IN2011MN02630A
申请日:
2011.12.07
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
The present invention relates to a resolution process of ( + ) -methyl phenyl[4-[4-[[[4"-(trifluoromethyl)-2-bipheny-lyl]carbonyl]amino]phenyl]-l-piperidinyl]acetate to isolate the MTP (microsomaltriglyceride transfer protein) inhibitor methyl(2S)-phenyl[4-[4-[[[4"-(trifluoromethyl)-2-biphenylyl]carbonyl]amino]phenyl]-l-piperidinyl]-acetate and an epimerisation procedure for reacemizing methyl (2R)-phenyl[4-[4-[[[4"-(trifluoromethyl)-2-biphenylyl]carbonyl]amino]phenyl]-l-piperidinyl]acetate.
