Matthew J. Bernett,Seung Yup Chu,John R Desjarlais,Sher Bahadur Karki,Gregory Alan Lazar,Erik WeiKing Pong,John O. Richards,Eugene Alexander Zhukovsky
申请号：
US13959587
公开号：
US09803020B2
申请日:
2013.08.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention describes antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an FcgγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the antibodies of the invention.
