Desjarlais, John R.,Chu, Seung Yup,Pong, Erik Weiking,Karki, Sher Bahadur,Bernett, Matthew J.,Lazar, Gregory Alan,Zhukovsky, Eugene Alexander
申请号：
AU2009206506
公开号：
AU2009206506B2
申请日:
2009.01.21
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention describes humanized antibodies that target CD40, whereinthe antibodies comprise at least one modification relative to a parent antibody,wherein the modification alters affinity to an FcγR or alters effectorfunction as compared to the parent antibody. Also disclosed are methods of usingthe antibodies of the invention.
