Eugene Alexander Zhukovsky;Matthew J. Bernett;John R. Desjarlais;Seung Yup Chu;Gregory Alan Lazar;Erik WeiKing Pong;John O. Richards;Sher Bahadur Karki
发明人:
Matthew J. Bernett,Seung Yup Chu,John R. Desjarlais,Sher Bahadur Karki,Gregory Alan Lazar,Erik WeiKing Pong,John O. Richards,Eugene Alexander Zhukovsky
申请号:
US12377251
公开号:
US08524867B2
申请日:
2007.08.14
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an FcyR or alters effector function as compared to the parent antibody, and methods of using the antibodies.